The note is devoted to analysis of the current investment conditions, the issues of investment increase in the regions of Uzbekistan. The paper shows that one of the key factors limiting the attraction of investment to the regions, is a centralized authority to access investments in the region, including foreign ones. The problems referred to in this Option paper to be addressed were identified in the course of practical work with investors. The paper includes the recommendations for improving state regulation of investment activity and a phased transfer of powers to the regions of Uzbekistan.